This is an extended version of our article What exactly is Detox… . If you haven’t read it yet, or if you just want to get some brief information on the topic, we recommend you start there.
PPC can be used very well for intoxications of the liver
The most important organ that contributes to the detoxification of the body is the liver. The keyword “detox” is used to refer to many active ingredients today. Whether they actually work is often only attributed to empirical knowledge. The active ingredient PPC in contrast has been very well researched with regard to its ability to support the liver in its detoxification performance.
The liver often suffers silently. Unlike other organs, the possible symptoms of liver disease are usually diffuse and ambiguous. These include fatigue, lethargy, irritability, sleep disorders, nausea, vomiting, dizziness, abdominal pain, fever, flatulence, diarrhoea, constipation, weight loss, itching, muscle and joint pain, loss of appetite, food intolerance, headaches, concentration and memory problems, asterixis (flapping tremor), bleeding tendencies, anaemia as well as dark urine, clay-like or white stool and impotence, to name but a few symptoms.
This list reads almost like a list of commonplace symptoms and health problems that each of us may have from time to time. This is why we often only intervene when a liver disease is already advanced and reflected in clinical signs such as enlargement of the liver and/or spleen, jaundice, spider nevi and ascites, as well as pathological laboratory findings.
Intoxications of the liver are often caused by, for example, bacterial colonisation in the intestine or diseases such as tuberculosis, by medication, toxic environmental conditions (e.g. through heavy metals, solvents, radioactivity) as well as drugs, malnutrition and alcoholic beverages. Medication necessary for survival, such as cytostatics or radiation in cancer therapies, can lead to impairment of liver function.
Highly enriched PPC from the soybean can be effective in these indications both preventively and therapeutically. There are numerous publications and studies on liver toxicity and positive PPC effects. A few of them should be mentioned here, which illustrate the potential of cell rejuvenation therapy (CRT) of the Network of Extended Medicine for this symptomatology, especially in cases of more severe poisoning.
- K.-J. Gundermann and co-authors [1 a+b] have summarised the results of 219 experimental studies with 50 different models and 8 animal species in a review on intoxication in 2011. There are a number of chemical substances and medical agents whose negative consequences can be mitigated or even eliminated by antioxidative, cytoprotective and regenerative therapy with PPC. Ethanol and tetrachlorocarbons have been studied very intensively, and the effects of PPC on fatty liver and fatty liver hepatitis have also been closely examined.
- Among the potentially liver-damaging drugs, the best known and most frequently used are paracetamol, tetracycline, indomethacin, diclofenac, cyclosporine A as well as anaesthetics, and radiation-induced intoxications for physical measures. In China, for example, PPC is included as a positive control in many trials of a new drug. For example, in a study published in 2011 [2] the effect of polyprenols in a plant extract (TPs) was compared with PPC. See also the two histological images of TPs and PPC.
Tratment with TPs 
Treatment with PPC
- The effect of PPC on intoxications caused by anti-tuberculosis drugs, which are known to cause liver damage, has also been very well studied.
- Particularly impressive is perhaps the effect of PPC during and after chemotherapy. Wu and colleagues already investigated the hepatoprotective effect of PPC in the treatment of lung cancer with cytostatic drugs in 1998. The ALT value in serum increased in 78.2% of patients without PPC, and in only 41.4% of patients with PPC [3]. In acute lymphoblastic leukaemia in children, the number of interruptions to chemotherapy in days due to high ALT levels caused by PPC was significantly reduced [4].
- Further investigations were also performed with heavy metal loads from uranium, lead and mercury [5].
- Last but not least, the effect of PPC on people who consumed anabolic steroids was also investigated. In this case, all the values measured under PPC after eight weeks of treatment had dropped sharply and even returned to normal [6].
Administration and dosage
PPC can be administered both orally and intravenously. The dosage of oral administration in capsule form can be 900 mg to 1.8 g daily, depending on whether PPC is administered preventively or therapeutically (2 x 1 or 2 x 2 capsules of Memphosan daily).
The dosage of the intravenous administration can also vary considerably. With the newly developed Nano PPC 500, 7-10 sessions with 500 mg PPC should be sufficient (can also be used by alternative practitioners). With the old formulation of PPC with deoxycholic acid as solubilizer, which cannot be injected directly like the Nano PPC 500 but has to be infused with 5% glucose solution to avoid side effects or intolerances caused by deoxycholic acid, 1-2 g PPC per infusion are recommended depending on the severity of intoxication. The exact dosage can only be carried out by a treating physician, we only provide the values of experienced practitioners here.
Conclusion
Almost everyone today is increasingly exposed to substances that can affect the liver’s ability to metabolize and excrete toxins. PPC is a substance produced naturally in the body that is able to improve the detoxification performance of the liver and protect the liver itself from overstraining.
Literature:
1a] Activity of essential phospholipids (EPL) from soybean in liver diseases.
Gundermann KJ, Kuenker A, Kuntz E, Droździk M.Pharmacol Rep. 2011;63(3):643-59. doi: 10.1016/s1734-1140(11)70576-x.PMID: 21857075 Free article. Review.
1b] Essential phospholipids in fatty liver: a scientific update.
Gundermann KJ, Gundermann S, Drozdzik M, Mohan Prasad VG.Clin Exp Gastroenterol. 2016 May 5;9:105-17. doi: 10.2147/CEG.S96362. eCollection 2016.PMID: 27217791 Free PMC article. Review.
2] Polyprenols from Taxus chinensis var. maireiprevent the development of CCl4-induced liver fibrosis in rats JinhuiYuabYanbinWangbHuaQianbYunpengZhaoaBentongLiubChengxinFua
3] Wu M et al: Chinese Clin. Oncol. 1998; 25: 663–665
4] Pawelec K et al: Pediat. Rakt. 2002, 10; 49–53
5] Shpagina LA, Bobrov CV: Ter. Arkh. 2004; 76: 63–66
6] Pagonis TA et al: Clin. Toxicol. 2008; 46: 57–66